Ask Me About My Estrogen

Hair Loss and Exhaustion in Perimenopause

In this episode of Ask Me About My Estrogen, Charlotte and Megan get real about two of perimenopause's most frustrating symptoms: hair loss and bone-deep exhaustion. They break down the hormonal science behind both — why your ponytail is thinning, why you're wired but can't sleep, and why this fatigue is nothing like ordinary tiredness. Plus, what you can actually do about it. Raw, honest, and relatable as always.

Perimenopause Check-In: Managing Rage, Sleep Loss, GLP-1 Microdosing & More

In this real-life check-in, Charlotte and Megan get honest about where they're at — no experts, just two friends navigating perimenopause in real time. They cover the ongoing rage, Charlotte's sleep struggles, GLP-1 microdosing updates, and why strength training first thing in the morning has been a game changer. They also share listener feedback that genuinely moved them, including one woman who got her first-ever bloodwork done after finding the podcast. Plus: the Bluey book that perfectly captures mom life, pirate parenting, and why a medicine ball might be the best rage therapy nobody's talking about.

The Perimenopause Supplement Guide: What to Take and Why With Special Guest Heidi Harris

Megan and Charlotte sit down once again with dietitian Heidi Harris to tackle one of the most overwhelming topics for women in perimenopause — supplements. With thousands of options on the market and social media pushing everything from hormone-balancing glitter gummies to maca root, Heidi cuts through the noise and brings the science back to basics.

Sex, Desire & Perimenopause

Charlotte and Megan talk to Dr. Dori Gatter about all things sex and perimenopause. 

Nutrition Best Practices with Heidi Harris

We are back with Heidi, this time discussing nutrition and how our needs change during perimenopause. 

High Cholesterol During Perimenopause

 
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Your Hormones and Your Heart: What Every Woman Needs to Know About Cholesterol
Your hormones and your heart are more connected than you think — and perimenopause may be changing your cardiovascular risk right now, without you even knowing it.
In this episode, Charlotte and Megan break down everything women need to know about cholesterol, estrogen, and heart health: why heart disease is still the #1 killer of women in the US, how declining estrogen during perimenopause shifts your cholesterol profile, what your numbers actually mean, and why "you're fine" from your doctor isn't always enough. Whether you're in your 30s, 40s, or beyond, this is the conversation about women's cardiovascular health that should have been happening all along.
In this episode:
How estrogen protects your heart — and what happens when it declines
LDL, HDL, triglycerides, ApoB, and Lp(a) explained simply
Updated cholesterol screening guidelines for women
The cholesterol myths that could be putting your health at risk
What to ask your doctor at your next appointment
Heart disease. Cholesterol in women. Perimenopause and heart health. Women's cardiovascular health. Cholesterol screening guidelines. Estrogen and cholesterol. Preventative health for women.

Exercise Best Practices During Perimenopause With Heidi Harris

Your body didn't break — the rules just changed. In this episode, Charlotte and Megan sit down with registered dietitian and strength coach Heidi Harris to cut through the noise on perimenopause, metabolism, and why your old routine stopped working. From protein targets and heart rate zones to the supplements actually worth taking, this is the practical, no-BS conversation you've been waiting for.

Perimenopause + Aging Gracefully with a Plastic Facial Surgeon and Aesthetician

Why Am I So Angry? Perimenopause Rage, Hormones & What Actually Helps

The Big Theme: Perimenopause-related rage is real, common, and rooted in biology — not a character flaw.
The Science: Estrogen acts as a neuromodulator, affecting serotonin, dopamine, and GABA (the brain's calming chemical). When estrogen fluctuates during perimenopause, emotional regulation suffers. Declining progesterone removes another layer of calm. The amygdala becomes more reactive, meaning small stressors can feel like major threats.
Key Takeaways:
It's the variability of estrogen — not just the decline — that drives mood volatility
Rage often isn't intellectual; it's hormone-driven and can feel out-of-body
Women are socialized to feel shame about anger, which compounds the problem
Rage can also signal depression or thyroid issues, so see a clinician if it feels constant or scary
Practical Strategies Discussed:
Sleep hygiene, blood sugar stability, strength training, and reducing alcohol
Nervous system tools like paced breathing and cold water on the face
Cycle tracking to predict and prepare for rage windows
Medical options, including SSRIs/SNRIs and hormone therapy
Setting boundaries and reducing invisible labor
The Closing Thought: Some midlife rage may actually be clarity — a dropping away of people-pleasing and a clearer view of what you've been carrying. Dysregulation is treatable, and you don't have to white-knuckle your way through midlife.

Cycle Syncing With Amy Dave

Ever feel like your body is working against you — one week you're crushing it, and the next you can barely think straight? In this episode, we're sitting down with Amy Dave from The Wealth of Wellness to talk all things cycle syncing during perimenopause.
Amy breaks down how fluctuating hormones impact your mood, energy, focus, and that pre-period rage — and how to actually work with your cycle, even when it's unpredictable. We cover how to track your cycle, when to adjust your workouts and diet, and simple strategies you can start using right away.
Whether your cycles are regular or all over the place, this one's for you.
 
Music by FreeMusicForVideo from Pixabay